Showing posts with label study findings. Show all posts
Showing posts with label study findings. Show all posts

Wednesday, 11 June 2014

Placebo? Mind over Muscle at Harvard

Wisdom Quarterly; Alia Crum, Ellen Langer (Harvard), Psychological Science (18, 2: 165-171)
(Chauncey McDermott) Mind over matter: "You can do it, Duffy Moon!"

Mind-Set Matters: Exercise and the Placebo Effect
ABSTRACT—In a study testing whether the relationship between exercise and health is moderated by one’s mindset, 84 female room attendants working in seven different hotels were measured on physiological health variables affected by exercise. Those in the informed condition were told that the work they do (cleaning hotel rooms) is good exercise and satisfies the Surgeon General’s recommendations for an active lifestyle. Examples of how their work was exercise were provided. Subjects in the control group were not given this information. Although actual behavior did not change, 4 weeks after the intervention, the informed group perceived themselves to be getting significantly more exercise than before. As a result, compared with the control group, they showed a decrease in weight, blood pressure, body fat, waist-to-hip ratio, and body mass index. These results support the hypothesis that exercise affects health in part or in whole via the placebo effect.

Shhhh. These are just sugar pills.
The placebo effect is any effect that is not attributed to an actual pharmaceutical drug or remedy, but rather is attributed to the individual’s mind-set (mindless beliefs and expectations).

The therapeutic benefit of the placebo effect is so widely accepted that accounting for it has become a standard in clinical drug trials to distinguish pharmaceutical effects from the placebo effect and the placebo effect from other possible confounding factors, including spontaneous remission and the natural history of the condition (Benson & McCallie, 1979; Brody, 1980; Nesbitt Shanor, 1999; Spiro, 1986). Kirsh and Sapirstein (1998), in a meta-analysis of 2,318 clinical drug trials for antidepressant medication, found that [only] a quarter (25.16%) of the patients’ responses were due to the actual drug effect, another quarter (23.87%) were due to the natural history of depression, and half (50.97%) were due to the placebo effect.

Scholar Shelly Brown: "Bridging science and religion" (news.harvard.edu)
  
Powerful love medicine (glucose, FD&C red)
The placebo effect extends much further than medications or therapy: Subjects exposed to fake poison ivy developed real rashes (Blakeslee, 1998), people imbibing placebo caffeine experienced increased motor performance and heart rate (and other effects congruent with the subjects’ beliefs and not with the pharmacological effects of caffeine; Kirsch & Sapirstein, 1998), and patients given anesthesia and a fake knee operation experienced reduced pain and swelling in their ‘‘healed’’ tendons and ligaments (Blakeslee, 1998). More generally, studies suggest that 60 to 90% of drugs and other therapies prescribed by physicians depend on the placebo effect for their effectiveness (Benson & Freedman, 1996; Nesbitt Shanor, 1999).

The placebo effect does not have to involve inert pills or sham procedures. Symbols, beliefs, and expectations can elicit powerful physiological occurrences, both positive and negative (Hahn & Kleinman, 1983; Roberts, Kewman, & Mercie, 1993).

Prof. Ellen Langer, Harvard University
For example, the mere presence of a doctor increases patients’ blood pressure (the ‘‘white coat effect’’), reinterpreting pain in nonthreatening ways (e.g., as sensations) prompts patients to take fewer sedatives and leave the hospital sooner; and the health decline of cancer patients often has less to do with the actual course of the illness and more to do with their negative expectations regarding the disease (Langer, 1989).

EXERCISE AND THE PLACEBO EFFECT
As the most common health threats are now infectious rather than chronic, remedies have also changed. Doctors now prescribe behavioral changes such as exercise for chronic diseases like diabetes, heart disease, and even cancer. We wondered whether the well-known benefits of exercise are in whole or in part the result of the placebo effect. A positive finding would speak to the potentially powerful... More

Tuesday, 4 March 2014

Study: cheese, meat, eggs = Cancer (audio)

Amber Larson, Pat Macpherson, Wisdom Quarterly
Vegan beauty Alicia Silverstone wants moms to loan their breasts (news.softpedia.com)

Winner: "Best Vegan Pizza" using melting, dairy-free Daiya cheese (peta.org)
One Burger King Triple Whopper has 49 grams of dead animal protein, which is the maximum recommended daily total for a 130-pound adult (Joe Raedle/Getty Images).
  
Big Macs are made of cancer-causing flesh.
Middle-aged people with diets high in animal flesh protein -- such as meat, poultry, eggs, milk, and cheese -- face a dramatically increased risk of dying from cancer compared with those who eat low animal protein diets, according to a University of Southern California study published today in the journal Cell Metabolism.

If only cows lived on a compassionate planet
The study found 50 to 65-year-olds who consumed a "high-protein" diet -- meaning they got 20 percent or more of their calories from animal sources of protein -- were four times more likely to die from cancer, compared with those who consumed less than 10 percent of their daily calories in animal protein.
Lines at Vegan Pizza Contest, Animal Advocacy Museum, Throop UU, summer 2013 (WQ)
  
Vegan pizza rules (WQ)
A press release accompanying the study called that "a mortality risk factor comparable to smoking." The risk of early death from all causes soared by 74 percent among the high-protein consumers, researchers found.
 
But the picture changes for those over 65. For them, it appears that a moderate-to-high protein diet [not necessarily from animal sources] actually reduces cancer and overall mortality and is helpful in preventing age-dependent weight loss and malnourishment.
 
Researchers focused their study on a national cross-section of 6,381 people 50 and older who were tracked for nearly 20 years.
 
They also found that among all the age groups studied, a diet high in animal protein increases insulin production and the risk of dying from diabetes-related causes.
 
The higher risk of cancer and overall death among the middle-aged and the increase in diabetes deaths were "either abolished or attenuated if the proteins were plant derived," the study said.
 
Go veg for bliss (WQ/Larson)
Various health agencies recommend that daily intake of animal protein should be about 0.8 grams per kilogram. So a 130-pound adult should eat [no more than] between 45 and 50 grams of animal protein per day. A 160-pound adult should eat between 60 and 65 grams per day.
 
How much protein is that? It sounds like a lot. Here is some help in calculating:
Los Angeles bans e-cigarettes in smoke-free areas
Electronic cigarettes will be prohibited in L.A. parks, restaurants, and "meat-market" pick up bars under an ordinance approved today (3-4-14) by the Los Angeles City Council.